Nanoparticle Surface Protein Analysis


Characterize nanoparticles and extracellular vesicles (EVs) from almost any fluid and biofluid - from plasma to tissue culture media

Nano-flow cytometry is the latest development for protein analysis on nanoparticles. Using light scattering and labelled fluorescent antibodies, our analysis allows direct, single-particle physical and bio-chemical measurements of nano-sized entities on a single platform.
奈米表面蛋白分析 NanoFCM | Reliance Biosciences | Molecular diagnostics via exosome
奈米表面蛋白分析 NanoFCM Size Distribution_Reliance Biosciences_Molecular diagnostics via exosome
Fig. 1. Detectable range of EVs

NanoFCM Case Study

Using fluorescence and measurements of particle size and concentration to determine breast cancer HER2 status

HER2 is a growth-promoting protein found on 15-20% of breast cancer cells. These cells tend to grow and spread faster than normal breast cells. In the following analysis, HER2 antibodies were labeled exosomes from MCF7 cell line (HER2-Negative), 82T primary cell line (HER2-Positive metastatic site), AU565 cell line (HER2-Positive), and healthy donor (HD), were tested with PBS (blank) as control. The figure below shows HER2-Positive signals above the cut-off for 82T and AU565. The other signals below cut-off indicate HER2-Negative.
Characterizing exosomes奈米表面蛋白分析 NanoFCM Nanoparticle Surface Protein Case Study_Reliance Biosciences_Molecular diagnostics via exosome
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Publication Library

Learn more about Nano-flow cytometry (NanoFCM) applications in industry and other research uses in these published papers.

Sample Preparation Instructions

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#奈米表面蛋白分析 #Nanoparticle Surface Protein Analysis #NanoFCM #Extracellular Vesicle #exosome #exosomes