Our approach
Exosomes are nano-sized vesicles secreted by cells, including specific disease-related cells, and control biological manifestations through blood circulation. The nucleic acids encapsulated by these exosomes and the protein components of the source cells have been proven to contain a wealth of clinically relevant diagnostic biomarkers.
Current Approaches
Our Approach using Exosomes
- abundant in blood (109/mL plasma)
- secreted by neurons
- can cross blood-brain barrier (BBB)
- exosomes: 30-150nm diameter
- contain disease-specific cargo (protein, mRNA, RNA, DNA)
Exosomes
EXOSOMES (30-150nm in diameter) are bio-nanoparticles secreted from cells, including disease-specific cells, and make their way into the blood circulation. They contain valuable nucleic acids and proteins from their cells of origin and have proven to contain rich source of clinically relevant diagnostics targets. With a billion exosomes in a millimeter of plasma, exosomes’ diagnostic values are demonstrated in cardiovascular, cancers and a range of life-threatening diseases.
