Our Approach using Exosomes
- abundant in blood (109/mL plasma)
- secreted by neurons
- can cross blood-brain barrier (BBB)
- exosomes: 30-150nm diameter
- contain disease-specific cargo (protein, mRNA, RNA, DNA)
EXOSOMES (30-150nm in diameter) are bio-nanoparticles secreted from cells, including disease-specific cells, and make their way into the blood circulation. They contain valuable nucleic acids and proteins from their cells of origin and have proven to contain rich source of clinically relevant diagnostics targets. With a billion exosomes in a millimeter of plasma, exosomes’ diagnostic values are demonstrated in cardiovascular, cancers and a range of life-threatening diseases.