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Our approach

外泌體(exosomes)是由細胞所分泌的奈米小囊泡,其中也包括疾病相關的特定細胞,並且會透過血液循環控制生物表現。這些外泌體所包裹的核酸與來源細胞的蛋白質成分已被證實包含了豐富的臨床相關診斷的生物指標。

Current Approaches

Exosomes - our Technology | current market PET scan for diagnosis of Alzheimer's disease
Exosomes - our Technology | current market spinal tap for diagnosis of Alzheimer's disease

Our Approach using Exosomes

Exosomes in the blood - our Technology | Reliance Biosciences
  • abundant in blood (109/mL plasma)
  • secreted by neurons
  • can cross blood-brain barrier (BBB)
    • exosomes: 30-150nm diameter
  • contain disease-specific cargo (protein, mRNA, RNA, DNA)

Exosomes

EXOSOMES (30-150nm in diameter) are bio-nanoparticles secreted from cells, including disease-specific cells, and make their way into the blood circulation. They contain valuable nucleic acids and proteins from their cells of origin and have proven to contain rich source of clinically relevant diagnostics targets. With a billion exosomes in a millimeter of plasma, exosomes’ diagnostic values are demonstrated in cardiovascular, cancers and a range of life-threatening diseases.

Exosome diagram